In partnership with Penn Medicine, the Smilow Center for Translational Research served as the venue for the 21st Annual Harrison Society Luncheon. Harrison Society members attended in record numbers and heard remarks from Dr. J. Larry Jameson, Dean of the Perelman School of Medicine, and the CEO of the University of Pennsylvania Health System, Ralph W. Muller. Our speakers provided insight on the innumerable contributions Penn Medicine has made to the community and the world, while emphasizing how vital planned gifts have been to these efforts. Guests were also given the opportunity to meet current students at Penn Medicine, who served as invaluable resources for learning the inner workings of such an elite institution. The afternoon was a blend of laughter, discovery, connecting with old friends and new, with the entire occasion serving as a resounding thank you for everything Harrison Society members do for the University of Pennsylvania.